HOLI(RADIANCE) 3-MONTH SET

• 3 x holi(radiance) OptiMSM® + CERAMOSIDES™ 99g (Expiry: May 2026)
• GIFT: 1 x holi(water) Hyaluronic Pearl & Rose Essence 30ml (worth HK$348)

Agent Nateur holi(radiance) is a powerful, science-backed formula that combines two of nature’s most potent ingredients, MSM and phytoceramides, both of which are clinically shown to reduce signs of aging and significantly improve the appearance of skin firmness, tone, hydration, texture, fine lines, wrinkles and acne, to deliver glowing skin, lustrous hair and strong nails from the cellular level, whilst supporting healthy immune system and joints, void of any fillers or taste/texture enhancers.

Featuring OptiMSM®, the world's purest MSM, as well as CERAMOSIDES™, a patented active compound combining natural phytoceramides from wheat and an efficiency booster, digalactosyl-diglyceride (DGDG), a lipid essential for skin hydration, holi(radiance) helps build keratin and collagen for healthy hair, skin and nails, bring hydration to the skin via the bloodstream, restore the skin barrier, improve dryness, fine lines and wrinkles, and support the immune system, connective tissues, joints and cartilage.

MSM, Methylsulfonylmethane, is a naturally occurring form of sulfur found in all living organisms, and the third most abundant substance in our body. It is essential for many different functions in the body, including supporting proper cell structure and the immune system, reversing free-radical damage to cells, and repairing connective tissue. It is also known as the "Beauty Mineral" because of its potent anti-aging and skin-enhancing properties, in particular its collagen and keratin boosting effect. However, as we age, the concentration of MSM in our bodies naturally decreases, making it more difficult for our bodies to generate new cells, and most people are not getting enough sulfur in their diets.

OptiMSM® used in holi(radiance) is biomimetic, meaning it is exactly identical to MSM found naturally in the human body. It is also the only MSM that uses a proprietary four-stage distillation process for purification and third party testing to ensure purity, quality, and consistency.

Supplementing with OptiMSM® can provide the following benefits:

• Improves Signs of Skin Aging Such As Firmness, Texture, Fine Lines & Wrinkles
  MSM is amazing for combatting the signs of aging because it acts as a sulfur donor to keratin, a key structural protein that provides strength to hair and skin. It also supports the production of collagen, glutathione and glucosamine, which help maintain skin cell membrane flexibility and permeability, inhibit collagen breakdown, reduce the appearance of wrinkles, fine lines and sagging skin, and improve improves skin firmness, elasticity and hydration. A double-blind study found that those who supplemented with 3g of MSM daily for 16 weeks experienced significant improvements in skin firmness, tone, texture, and a reduction in crow's feet. Another study published in February 2020 found that participants who received 3g of MSM for 16 weeks had reduced facial wrinkles and skin roughness compared to the placebo group.
  
  
• Enhances the Benefits of Collagen Supplements
  The combination of MSM and collagen proved effective in promoting collagen synthesis, increasing skin moisture, and reducing signs of aging. A clinical study found that combining MSM and collagen significantly improved skin health. Results showed a 19% increase in dermis density, a 40% increase in skin hydration, a 12% reduction in skin roughness, and a 21% reduction in wrinkles.
  
  
• Reduces Inflammation
  Clinically studies have proven that MSM can reduce inflammation by lowering the production of pro-inflammatory cytokines, which can damage skin cells and cause signs of premature aging like wrinkles. It also helps reduce inflammation and excess fluids by facilitating the removal of metabolic waste products from the cells, which in turn, can result in a natural leaning out of the body. According to a review published in Nutrients in March 2017, there is also a link between obesity and inflammation, further supporting this suggestion that MSM could help with weight reduction.
  
  
• Promotes Hair Growth
  Research has suggested that MSM, rich in thiamine and biotin, help form bonds essential for strengthening the keratin in hair and influencing hair growth, while supporting strong, healthy skin and nails.
  
  
• Supports Connective Tissue Health
  Research shows that MSM extensively supports connective tissue health, preventing skin and general connective tissue stiffness in the body, making it a great supplement for both skin and joints health.
  
  
• Reduces Allergy Symptoms
  Researchers have determined that MSM can help alleviate the common symptoms of seasonal allergic rhinitis (SAR), such as sneezing, nasal congestion, sinus pressure, and coughing. One study shows that at 2.6g a day, MSM helped relieve both upper and lower respiratory symptoms, and people in the study reported increased energy levels throughout the study.
  
  
• Easing Osteoarthritis and Arthritis Symptoms
  One of the best known benefits of MSM is its effectiveness in easing osteoarthritis and arthritis symptoms. Clinically studies have supported the use of MSM for pain and inflammation associated with osteoarthritis, in particular knee problems, with results demonstrating a significant decrease in pain.
  
  

Ceramides are a type of lipid that are naturally found in the skin's stratum corneum. They play a crucial role in maintaining the skin's barrier function by filling in the gaps between skin cells, creating a strong and protective barrier that prevents moisture loss loss and blocks out irritants, bacteria and toxins to help maintain healthy, supple skin. Unfortunately, the level of ceramides in the skin naturally decreases as we age, which can then lead to dryness, tightness, wrinkles. Skin with a disrupted skin barrier is also more prone to sensitivity, redness, inflammations, and acne.

Supplementing with phytoceramides can help replenish the body with new ceramides, which permeate the bloodstream, go to the skin, and restore the skin barrier by filling in the crevices that deplete hydration and plumpness.

CERAMOSIDES™ used in holi(radiance) is composed of patented active ingredients combining natural phytoceramides from wheat and an efficiency booster, digalactosyl-diglyceride (DGDG), a lipid essential for skin hydration, to help restore the skin's natural ceramide levels from within, improve the skin's moisture retention ability, and strengthen the skin barrier function, rather than through topical application. Adopting a unique French extraction process, gluten gets removed, while the lipidic portion of the wheat kernel is left in concentrated form for maxmimum benefits.

Supplementing with CERAMOSIDES™ can provide the following benefits:

• Improves Skin Hydration, Water Retention and Moisture Levels
  Ceramides work by filling in the gaps between skin cells, creating a strong and protective barrier that prevents moisture loss and blocks out irritants, bacteria and toxins to help maintain healthy, supple skin, thus supplementing with phytoceramides help improve the damaged skin barrier and hydration levels. A randomized, double-blind, placebo-controlled clinical study, conducted on 40 women aged 30 to 60 years, shows an increase in skin hydration of 16% and a reduction in trans-epidermal water loss of 13% after 15 days of supplementation with just 30 mg of CERAMOSIDES™. Other studies demonstrated an increase in skin hydration of up to 65%.
  
  
• Reduces Wrinkles and Signs of Aging
  A hydrated, moisturized skin state has less visible fine lines and wrinkles. Clinical studies show that consuming CERAMOSIDES™ for only 15 days resulted in a 9% reduction in wrinkles, doubling to 18% after two months. Furthermore, skin elasticity improved by over 18% within 15 days and over 26% in just two months, according to another study, while other studies demonstrated a reduction in wrinkles of up to 22%. The European Journal of Pharmaceutics and Biopharmaceutics also confirmed that replenishing depleted ceramides can restore the skin barrier and have beneficial effects for skin health and skin aging.
  
  
• Improves Eczema, Atopic Dermatitis, Rosacea and Sensitive Skin
  Conditions such as eczema, atopic dermatitis, psoriasis, rosacea, and sensitive, aging skin are often marked by impaired skin barrier function, making the skin more susceptible to irritants, pollution, and bacterial attack, as well as inflammations. By increasing the overall ceramide levels in the skin, not only can it help with overall skin health and barrier function, but can also help improve the aforementioned skin conditions.
  
  

1. Dehydrated and dry skin
2. Fine lines & wrinkles
3. Aging Skin
4. Skin inflammations
5. Dull, uneven skin tone
6. Brittle nails
7. Hair loss
8. Osteoarthritis
9. Arthritis
10. Joints health